For example, May-Hegglin anomaly, Bernard Soulier syndrome and gray platelet syndrome can be seen with values close to 13 fl, Sebastian syndrome with values around 18 fl and Fechtner syndrome can reach values of 20 fl. Low MPV A low MPV means that platelets are smaller than average. There is some lab-to-lab variability in ranges due to differences in equipment, techniques, and chemicals used. If the MPV is very high, it may suggest a hereditary genetic disorder. MPV Normal Range The normal MPV range is around 7-12 fL (fL one femtoliter, a very small unit of blood). The MPV should be studied along with platelet count to give a better diagnosis. Mean platelet volume (MPV) is generated by an electronic cell counter, which indicates the average volume. If the cells are smaller than usual, you have a low MPV. It is rare and a visit to your doctor is recommended. Normal platelets measure 14 m in diameter on PBS. Mean platelet volume (MPV) is part of your blood test results. The platelet mean size is much bigger than normal range. Severe macrothrombocytes (> 13 fl in adults):.If the platelet count is in the normal range, the alteration is not something to be worried about. The MPV is interesting for diagnosis when the platelet count is altered to discern the possible cause. In many labs, values up to 12 fl are considered to be in the normal range. The platelet mean size is a bit bigger than normal range, but is not a matter for concern. Mild macrothrombocytes (12 - 13 fl in adults):.If the MPV is high and the platelet count is also high ( thrombocytosis) it is usually due to an infection or an inflammation.Ī high MPV increases the risk to suffer a heart disease.

If the MPV is high and the platelet count is in the normal range, it is usually due to hyperthyroidism or chronic myeloid leukemia. Interestingly, the MPV increased in mice within 8 hours after the production of. With autosomal recessive inheritance: Bernard Soulier syndrome. A high MPV value suggests the presence of increased thrombopoiesis.With autosomal dominant inheritance: May-Hegglin, Epstein, Fechtner and Sebastian syndromes.When the MPV is high, the platelet size is similar to RBC (Red Blood Cells) and it is followed by thrombocytopenia (low platelet count) it may suggest a congenital thrombocytopenia. If the MPV is high and platelet count is low ( thrombocytopenia) it may be due to a recovery after a severe bleeding or an ITP (immune thrombocytopenic purpura). The MPV values in patients with cervical cancer and control subjects were 8.6 ± 1.3 and 9.2 ± 0.9 fl, respectively. FPG, haemoglobin, and MPV in two groups are markedly different (p < 0.001). Low platelet count: ( thrombocytopenia) The clinical and laboratory characteristics of subjects with cervical cancer and control subjects are.It is possible to discern three different causes for a high MPV depending on the platelet count:

The MPV is usually higher when the production or destruction of platelets is also high. The MPV (Mean Platelet Volume) measures the average size in volume of the platelets in the blood.

Mpv lab value